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Department of Biotechnology

Dr. Kumaraswamy H MM.Sc., Ph.D,

Associate Professor
 

Area Of Research

Cell Signalling, Medicinal Plants, Anti-cancer Therapeutics

 

About the Faculty

Short note from the faculty

Awards

Sl No Award Name Award For Organization Year
1 Young Investigator Award Oral pesentation- Smoking induced DNA damage results in ATM dependent phosphorylation of Histone H2AX in pancreatic cancer American Pancreatic Association,USA 2014
2 CV Raman Post Doctoral Award Tenable in USA Post Doctoral Research UGC, New Delhi 2013
 

Journals Publications

 
Sl No Authors Title Impact Factor Publisher Year
1 H. Muktha, R. Sharath, Nagaraju Kottam, H.M. Kumaraswamy, S. Srinath. Carbon dots- A study of its cytotoxicity activity against HepG2 and MCF-7 cell lines 0 Materials Today: Proceedings. 2021-05-14
2 P. Meghana, Jain R. Sandeep Kumar, Telkar Sandeep, N. Prashanth, H.M. Kumaraswamy. Acetogenins as potential checkpoint-2 kinase inhibitors: an in silico analysis. 0 Journal of Proteins and Proteomics 2019-10-15
3 Supriya Srinivasan, Venkatakrishna Jala, Kumaraswamy Honnenahally, Jason Castellanos, Praveen Kumar Urolithin A prevents pancreatic tumor growth and increases survival by inhibiting PI3K/PDK1 and STAT3 signaling 9.1 Cancer Research 2018-11-10
4 Arunodaya Hosahalli Sumithregowda, Krishna Venkatarangaiah, Kumaraswamy Honnenahally, Vinaykumar Cytotoxicity and Oral Acute Toxicity Studies of Litsea glutinosa C. B (ROB) Stem Bark Ethanol Extract. 0 Pharmacognosy Journal 2017-08-01
5 Mahadevappa Paramesha, Chapeyil Kumaran Ramesh, Venkatarangaiah Krishna, H. Malleshappa Kumar Swa Effect of dehydroabietylamine in angiogenesis and GSK3- inhibition during wound healing activity in rats. 1.43 Springer: Med Chem Res 2014
6 Khadeer B. M. Ahamed Harish Basavanthappa Gowdru, Sharath Rajashekarappa Kumar Swamy H. Mal Molecular docking of glycogen synthase kinase3-b inhibitor oleanolic acid and its wound-healing activity in rats. 1.43 Springer: Med Chem Res 2012
7 Harish B. Gowdru, Shrath Rajashekarappa, Kumara Swamy H. Malleshappa, Katenahally R. Maruth In vitro regeneration of Inflorescence and callus enhancement of Celastrus paniculatus Willd. 1.4 Global Science Books: MAPSB 2011
8 R. Sharath, B.G. Harish, V. Krishna, B.N. Sathyanarayana and H.M. Kumara Swamy. Wound Healing and Protease Inhibition, Activity of Bacoside-A, Isolated from Bacopa monnieri Wettest. 2.66 Wiley Online Library:. Phytother Res. 2010
9 B.G. Harish., V. Krishna., H.S. Santhosh Kumar, B.M. Khdeer Ahamed, R. Sharath, H.M Kumaraswamy. Wound healing activity and docking of GSK3-β with lupeol isolated from Celastrus paniculatus Willd. 3.5 Elsevier: Phytomedicine 2008
10 Prabhakara, M. C., Naik, H. S. Bhojya, Krishna, V. and Kumaraswamy, H. M. Binding and Oxidative Cleavage Studies of DNA by Mixed Ligand Co(III) and Ni(II) Complexes of Quinolo [3,2-b]Benzodiazapine and 1,10-Phenanthroline 0.76 Taylor and Francis:Nucleosides, Nucleotides and Nucleic Acids 2007
11 B.M. Khadeer Ahamed, V. Krishna., Harish B.Gowdru., H. Raja Naika, H.M. Kumaraswamy, R. Sha Isolation of bactericidal constituents from the stem bark extracts of Grewia tiliaefolia Vahl 0.2 Academic Journals Inc:Research Journal of Medicinal Plants 2007
12 Kumaraswamy H.M., Krishna,V., Shankarmurthy,K., Abdul Rahiman,B, Mankani, K.L., Mahadevan,K Wound healing activity of embelin isolated from the ethanol extract of leaves of Embelia ribes Burm. 3 Elsevier: Journal of Ethnopharmocology 2007
13 Harish B. G, Krishna,V. Sharath R, H.M. Kumara swamy, Raja naika H., Mahadevan K. M. Antibacterial activity of celapanin, a sesquiterpene isolated from the leaves of Celastrus paniculatus Willd. 0.35 Int. J. Bio Med. Pharma. Sci 2007
14 Rajnaika H, Krishna .V, Vardaraj. N and Kumaraswamy H.M Microppropogation and Evaluation of Genetic variability among in Vitro regenerants of Nervalia zeylanica 0 GSB: Med. Aroma. Plant Sci. Biotech 2007

Books

 
Sl No Authors Title Publisher Year

Book Chapters

 
Sl No Authors Title Publisher Year

Conferences

 
Sl No Authors Title Organizer Year
1 Jason Castellanos, Supriya Srinivasan, Kumaraswamy Honnenahally, Chanjuan Shi, Michael N Vansaun, Da Oncogenic mutant KRAS modulates CREB activation through MEK-ERK and AKT signaling in pancreatic canc AACR:Cancer Research 2016
2 Kumaraswamy Honnenahally, Chanjuan Shi, Xi Chen, Jason Castellanos, Nipun Merchant, Timothy Blackwel γH2AX: A molecular marker of DNA damage response in smoking-induced pancreatic ductal adenocarc AACR; Cancer Res 2015
3 4.Jason Castellanos, Kumaraswamy Honnenahally, Chanjuan Shi, Nipun Merchant, Nagaraj Nagathihalli GM-CSF induces CREB signaling pathways and modulates tobacco carcinogen-induced pancreatic tumorigenesis. AACR: Cancer Research 2015
4 N. Nagathihalli, K. Honnenahally, H. Tanjore , F. Revetta , X. Chen ,J. Castellanos , C. Shi , N. Me Smoking-Induced DNA Damage Results in ATM-Dependent Phosphorylation of Histone H2AX in Pancreatic Ca wolterskluwer: Pancreas 2014

Articles

 
Sl.No Authors Title Publisher Year
1 Meghana P, Sandeep Kumar Jain R, Prashanth N & Kumaraswamy H M. Phytochemical profiling and screening of protective effects of Artabotrys odoratissimus on H2O2 induced oxidative stress in HEK-293 cells and erythrocytes. Botany Letters 2020-07-22
2 K.Lingaraju, R.B.Basavaraj, K.Jayanna, S.Bhavana, S.Devaraja, H.M.Kumaraswamy, G.Nagaraju, H.Nagabhu Biocompatible fabrication of TiO2 nanoparticles: antimicrobial, anticoagulant, antiplatelet, direct hemolytic and cytotoxic properties. Inorganic Chemistry Communications 2020-02-06
Sl No Title Funding Agency Co-Investigator Amount Status
1 Acetogenins Modulate ATM Signalling in Nicotine induced Chemoresistance in Pancreatic Cancer. DST Nil 2370000 COMPLETED
2 Embelin Can Modulate Ataxia-Telangiectasia Mutated (ATM) Signalling In Nicotine Induced Chemoresistant Pancreatic Cancer DST-SERB Nil 5210554 COMPLETED
3 Evaluation of Antiarthritic Property of the Bioactive Constituents of Embelia ribes Burm. UGC Prof. V . Krishna 914300 COMPLETED
4 Design and development of tumor targeted Embelin loaded nanoparticles. VGST-SMYSR Nil 500000 COMPLETED
Sl No Investigator Name Title Year
Sl No Name Title Research Degree
1 Sandeep Kumar Jain R Evaluation of Bioactive Principles from Garcinia talbotii Raizada. for their Therapeutic Potential Ph.D.
2 Meghana P Investigation and Screening of Bioactive ConstituentsFrom Artabotyrs odoratissimus R.Br. Ph.D.
3 Prashanth N Investigation of Therapeutic effect of Evodiamine on nicotine induced DDR in pancreatic cancer Ph.D.
4 Samartha J R Phytochemical profiling and Investigation of therapeutic value of wild vegetables Indigenous to Agumbe Rain Forests Ph.D.
Sl No Name Title of Thesis Research Degree Year Address EmailId